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Support wound healing
Enhance the patient experience

Chitogel is a post-operative hydrogel nasal dressing that is applied to the sinuses after endoscopic sinus surgery, and addresses a number of traditional sinus surgery challenges.1 1Ha T, Valentine R, Moratti S, Hanton L, Robinson S, Wormald P-J. The efficacy of a novel budesonide chitosan gel on wound healing following endoscopic sinus surgery. Int Firum Allergy Rhinol. 2018 Mar;8(3):435-443.2 2Athanasiadis T, Beule AG, Robinson BH, Robinson SR, Shi Z, Wormald PJ. Effects of a novel chitosan gel on mucosal wound healing following endoscopic sinus surgery in a sheep model of chronic rhinosinusitis. Larygoscope. 2008 Jun;118(6):1088-94. 

Chitogel for surgeons

Chitogel reduces ostial stenosis, minimises adhesions and has been shown to reduce the rate of revision surgery.

How to use Chitogel

Chitogel is easy, efficient and effective to use. Learn how to use Chitogel after endoscopic sinus surgery.

Chitogel for patients

Keep your patients informed about the benefits of Chitogel throughout their recovery journey.

Unique characteristics to improve patient outcomes

Chitogel improves wound healing through anti-inflammatory action and its ability to delay fibroblast migration.7 7Paramasivan S, Jones D, Baker L, Hanton L, Robinson S, Wormald PJ, Tan L. The Use of Chitosan-Dextran Gel Shows Anti-Flammatory, Antibiofilm, and Antiproliferative Properties in Fibroblast Cell Culture. Am J Rhinol Allergy. 2014 Sep-Oct;28(5):361-5.The dual effect of inhibiting inflammation and delaying fibroblast migration provides mechanisms for the anti-adhesion effect of Chitogel, as well as preserving the ostial patency of the sinus ostia.10 10Ha T, Valentine R, Moratti S, Robinson S, Hanton L, Wormald PJ. A blinded randomized controlled trial evaluating the efficacy of chitosan gel on ostial stenosis following endoscopic sinus surgery. Int Forum Allergy Rhinol. 2013 Jul;3(7):573-80.  

Chitogel also improves the speed of wound epithelialization, with studies showing that this epithelium recovers its ciliated surface, as shown on electron microscopy, significantly faster than where no gel has been used.2 2Athanasiadis T, Beule AG, Robinson BH, Robinson SR, Shi Z, Wormald PJ. Effects of a novel chitosan gel on mucosal wound healing following endoscopic sinus surgery in a sheep model of chronic rhinosinusitis. Larygoscope. 2008 Jun;118(6):1088-94.This indicates that Chitogel enhances epithelial migration and subsequent functionality, thereby improving the healing time and functioning of the mucosa and contributing to the increased ostial patency when using Chitogel.1 1Ha T, Valentine R, Moratti S, Hanton L, Robinson S, Wormald P-J. The efficacy of a novel budesonide chitosan gel on wound healing following endoscopic sinus surgery. Int Forum Allergy Rhinol. 2018 Mar;8(3):435-443.

Additionally, recent clinical research demonstrates that Chitogel significantly increases the abundance of commensal bacteria Corynebacterium accolens and Cutibacterium acnes forming the sinus microbiome, resulting in a healthier sinus environment.9 9Megow, A, Alsuliman Y, Bouras G, et al. Chitogel following endoscopic sinus surgery promotes a healthy microbiome and reduces postoperative infections. Int Forum Allergy Rhinol. 2022;1-15.

The importance of the microbiome in the sinonasal mucosal environment has been increasingly recognized, and is known to influence long-term sinus health and the need for revision surgery. A recent retrospective observational study demonstrated a significant reduction in revision surgeries among patients who underwent ESS with Chitogel, suggesting that use of Chitogel can improve long-term patient outcomes.16 16Barber JM, Bouras G, Robinson GS and Robinson SR. Chitogel improves long-term health economic outcomes following endoscopic sinus surgery in severe chronic rhinosinusitis patients. Front. Health Serv. 2024; 4:1196499. doi: 10.3389/frhs.2024.1196499.

Benefits of Chitogel

Chitogel reduces ostial stenosis, minimises adhesions and acts as an adjunct in the natural healing process.

Supports healing

Enhances wound healing and is shown to promote healthy sinuses1 1Ha T, Valentine R, Moratti S, Hanton L, Robinson S, Wormald P-J. The efficacy of a novel budesonide chitosan gel on wound healing following endoscopic sinus surgery. Int Forum Allergy Rhinol. 2018 Mar;8(3):435-443.9 9Megow, A, Alsuliman Y, Bouras G, et al. Chitogel following endoscopic sinus surgery promotes a healthy microbiome and reduces postoperative infections. Int Forum Allergy Rhinol. 2022;1-15

Controls bleeding

Controls minimal bleeding after sinus surgery3 3Chandra RK, Conley DB, Haines GK, 3rd, Kern RC. Long-term effects of FloSeal packing after endoscopic sinus surgery. American journal of rhinology. 2005;19(3):240-2434 4Kokkevold PR, Lew DS, Ellis DG, Bertolami CN. The effect of chitosan on lingual haemostasis in rabbits. J Oral Maxillofac Surg 1991; 49858-86311 11FDA 510K, Chitogel Endoscopic Sinus Surgery Kit, K172179.510K, Summary.Final

Prevents scarring

Prevents adhesions between mucosal surfaces in the nasal cavity. 5 5Costain DJ, Kennedy R, Ciona C, McAlister VC, Lee TD. Prevention of postsurgical adhesions with N, O-carboxymethyl chitosan: examination of the most efficacious preparation and the effect N, O-carboxymethyl chitosan on postsurgical healing. Surgery. 1997 Mar;121(3):314-9.10 10Ha T, Valentine R, Moratti S, Robinson S, Hanton L, Wormald PJ. A blinded randomized controlled trial evaluating the efficacy of chitosan gel on ostial stenosis following endoscopic sinus surgery. Int Forum Allergy Rhinol. 2013 Jul;3(7):573-80.11 11FDA 510K, Chitogel Endoscopic Sinus Surgery Kit, K172179.510K, Summary.Final

Healthcare Savings

Shown to reduce the rate of revision surgery, leading to health system efficiencies and cost savings.16 16Barber JM, Bouras G, Robinson GS and Robinson SR. Chitogel improves long-term health economic outcomes following endoscopic sinus surgery in severe chronic rhinosinusitis patients. Front. Health Serv. 2024; 4:1196499. doi: 10.3389/frhs.2024.1196499.

Supported by globally renowned surgeons and their patients

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years of research and evidence
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surgeon & patient testimonials

Surgeon and patient testimonials

"My patient’s nose looked great 2 weeks postop. The ostia are patent and there is no scarring"
"It's been life changing for me. Every surgeon should be using it"
"The gel gives the best results in a few months, and you will have an ‘a-ha' moment when this happens"
"It fully absorbed after 10 days and the patient continues to improve"
"It’s great that you have enough gel for both sides"
"I found the product easy to use"
"Just being able to focus, without that pressure behind my eyes and in my nose cavity... everything is clear. It is lovely"
"It's nice just to be able to lie down to sleep, and just live a normal life".